The Stoltz Group
Natural Product Synthesis and Synthetic Methodology
California Institute of Technology • Pasadena, California


• The group's latest full paper, titled "The Palladium-Catalyzed Aerobic Kinetic Resolution of Secondary Alcohols: Reaction Development, Scope, and Applications" has been published in Chemistry - A European Journal and can be found here.
• The group's latest publication titled "Expedient synthesis of 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones via one-pot aryne acyl-alkylation/condensation" has been published in Organic and Biomolecular Chemistry and can be found here.
• The group's latest publication titled "Catalytic Enantioselective Stereoablative Alkylation of 3-Halooxindoles: Facile Access to Oxindoles with C3 All-Carbon Quaternary Stereocenters" has been published in Angewandte Chemie and can be found here.
• The Stoltz Group's intramural softball team won the league championship! Click here to find the team picture!
• The group's latest publication titled "Unusual Allylpalladium Carboxylate Complexes: Identification of the Resting State of Catalytic Enantioselective Decarboxylative Allylic Alkylation Reactions of Ketones" has been published in Angewandte Chemie and can be found here.
• Brian was recently awarded the Tetrahedron Young Investigator Awards for Organic Synthesis for 2010. Congratulations!
• The groups latest review titled "Enantioselective Protonation" has been published in Nature Chemistry and can be found here.
• The group's publication titled "A Concise Total Synthesis of (-)-Quinocarcin via Aryne Annulation" has been featured in Synfacts, 2009, 708. The article can be found here.
• The group's synthesis of (+)-Cassiol has been featured in Synfacts, 2009, 712. The article can be found here.
• The group's latest publication titled "An efficient synthesis of the carbocyclic core of zoanthenol" has been published in Tetrahedron and can be found here.
• Brian was recently awarded the Raymond and Beverly Sackler Prize in the Physical Sciences. Congratulations!
• The group's latest publication titled "Synthetic efforts toward cyathane diterpenoid natural products" has been published in Nat. Prod. Rep. and can be found here.
• The group's latest publication titled "Unexpected decarbonylation during an acid-mediated cyclization to access the carbocyclic core of zoanthenol" has been published in Tetrahedron Lett. and can be found here.
• The group's publication titled "Palladium-Catalyzed Enantioselective Oxidation of Chiral Secondary Alcohols: Access to Both Enantiomeric Series" has been featured in Synfacts, 2009, 121. The article can be found here on the Synfacts page.
• Take a look at the group's three latest publications in Org. Synth. Titled "Preparation of (S)-2-Allyl-2-methylcyclohexanone", "Preparation of (S)-tert-ButylPHOX", and "The Direct Acyl-Alkylation of Arynes. Preparation of Methyl 2-(2-AcetylPhenyl)Acetate." They can be found here.
• The group's publication concerning "A Concise Total Synthesis of (-)-Quinocarcin via Aryne Annulation" has been featured in Chemistry World's Totally Synthetic column. Take a look here.
• The group's latest communication, "Progress toward the Synthesis of the Transtaganolide/Basiliolide Natural Products: An Ireland-Claisen Approach", has been published in Tetrahedron Lett. and can be found here.
• The group's latest paper, "Side Chain Chemistry Mediates Backbone Fragmentation in Hydrogen Deficient Peptide Radicals", has been published in J. Proteome Res. and can be found here.
• Take a look at the group's two latest papers! The "Catalytic Enantioselective Approach to the Eudesmane Sesquiterpenoids: Total Synthesis of (+)-Carissone" and the "Enantioselective Total Synthesis of (+)-Cassiol" have both been published in Org. Lett. and can be found here.
• Pictures from the group holiday party are now online, and can be found here.
• The latest publication from the group describing "A Concise Total Synthesis of (-)-Quinocarcin via Aryne Annulation" has been accepted to J. Am. Chem. Soc. and can be found here.
• The group's recent publication concerning "Catalytic Enantioselective Alkylation of Substituted Dioxanone Enol Ethers" has been featured in the November issue of Synfacts.
• The group's latest paper, titled "Structural Features and Reactivity of (Sparteine)PdCl2: A Model for Selectivity in the Oxidative Kinetic Resolution of Secondary Alcohols", has been published in J. Am. Chem. Soc. and can be found here.
Click here for archived news.
Chemistry 5a - Advanced Techniques of Synthesis and Analysis (Spring 2003)
Chemistry 41a - Organic Chemistry (Fall 2009)
Chemistry 250 - Advances in Pharmaceutical Research (Spring 2003)

Click here...The
magic is in the lab!
E-mail the maintainer of this site.